Anaplastic thyroid cancer (ATC) stands as the most formidable form of thyroid malignancy, presenting a persistent challenge in clinical management.Recent years have witnessed a gradual unveiling of the intricate genetic underpinnings governing ATC through next-generation sequencing.The emergence of this genetic landscape has paved the way for CORNE
Analysis of echo signal modulation characteristic parameters on aerial and space targets
Based on the scattering characteristic, the comparison of RCS (radar cross-section) at different positions of a target in the same direction of incidence can be obtained first by extruding or deleting part of the Winter Sports - Snowshoes entity.A simulation method of aerial&space targets echo characteristics (A&STEC) is proposed that is universal
The remote allosteric control of Orai channel gating.
Calcium Spacers signals drive an endless array of cellular responses including secretion, contraction, transcription, cell division, and growth.The ubiquitously expressed Orai family of plasma membrane (PM) ion channels mediate Ca2+ entry signals triggered by the Ca2+ sensor Stromal Interaction Molecule (STIM) proteins of the endoplasmic reticulum
Interplays of AMPK and TOR in Autophagy Regulation in Yeast
Cells survey their environment and need to balance growth and anabolism with stress programmes and catabolism towards maximum cellular bioenergetics economy and survival.Nutrient-responsive pathways, such as the mechanistic target of rapamycin (mTOR) interact and cross-talk, continuously, with stress-responsive hubs such as the AMP-activated protei